Can I run multiple trading strategies in one brokerage account?

Yes, if the platform enforces isolation. The clean architecture gives each strategy a sleeve — its own cash allocation, its own positions, its own P&L — inside the shared account. Every order is tagged with the strategy that placed it, checked against that sleeve's cash (so one strategy can't spend another's money), and fills route back to the sleeve that ordered. Done right, one strategy liquidating everything changes nothing for its neighbors, and you can add cash to, pause, or stop any single strategy independently. Without sleeve isolation, multiple strategies in one account silently fight: they double-buy the same ticker, sell each other's positions, and produce P&L nobody can attribute.